However, all these early games can use any of these devices...
Sorry, no. If the game's resources don't include the appropriate patch map, simply copying in an appropriate driver isn't going to work. Case-in-point: I have yet to see a version of KQIV with the Casio patch maps.
I see your point. The Game Blaster drivers actually copy a "patch.101" in addition to the CMS.DRV for KQ4 New, LSL2 New, SQ3 & PQ2. 101 is the Game Blaster patch designation. For the early versions of King's Quest IV and Leisure Suit Larry 2, the patch designations must be contained within the DRV file itself.
Hoyle & Silpheed contain native support for the Game Blaster (they include the patch on the disks themselves.) Hoyle 1 supports the Casio devices as does Leisure Suit Larry 3, so the none of the previous games can support a Casio device.
get an extra 10 sounds out of the MT-540, which are available instantly on the CT-460 or CSM-1 through a sysex hack.
You mean
program change messages?
I think that was the idea. I read something once to the effect that the extra sounds were not available through the controls on the keyboard, but only through midi. I thought maybe sysex was the cause, but it seems more likely that program change messages would allow access to the extra sounds. I wonder if Sierra used them.